Lecture Notes
   Workshops &
      Seminars

¡@

Genome Engineering Laboratory
Institute of Bioinformatics, National Yang-Ming University
Introduction | Announcement | Members | Projects | Resources | Contact

Chuan-Hsiung Chang (±i¶Ç¶¯)
Assistant Professor
Institute of Bioinformatics
National Yang-Ming University

E-mail: cchang@ym.edu.tw
Phone: 886-2-28267316
Fax: 886-2-28206754
Web: http://gel.ym.edu.tw/~chc/
Address: No. 155, Sec. 2, Li-Noun St.,
Taipei, Taiwan, 11221

Boss

PhD, Molecular Biology, University of Southern California
Postdoctoral Fellow/Postgraduate Researcher, Cancer Research Center,
    University of California, San Francisco
Researcher/Department Manager, Genomics Department,
    Biomedical Engineering Center, ITRI

American Association for Cancer Research (AACR) Young Investigator Award, 1999

Genomic organization of the Vibrio vulnificus chromosomes. The two chromosomes are depicted by circular representation. From the outside inward: the first and second circles show predicted protein-coding regions on the plus and minus strands, by role, according to the color code of the COG functional categories. Black denotes hypothetical, conserved hypothetical, and genes not included in COG functional categories. The third circle shows percentage G+C in relation to mean G+C for the chromosome. The fourth circle shows GC skew. The fifth circle shows super-integron (pink), capsular polysaccharide biosynthesis genes (green), cytotoxicity/hemolysin genes (red), iron acquisition genes (brown) and extracellular protease genes (blue). The sixth and seventh circles are tRNAs and rRNAs, respectively.

Recent Publications

Chen C-Y, Wu K-M, Chang Y-C, Chang C-H, Tsai H-C, Liao T-L, Liu Y-M, Chen H-J, Shen Arthur B-T, Li J-C, Su T-L, Shao C-P, Lee C-T, Hor L-I, and Tsai S-F. Comparative Genome Analysis of Vibrio vulnificus, a Marine Pathogen. (2003) Genome Research (In press).

Neve RM, Ylstra B, Chang C-H, Albertson DG, and Benz CC. ErbB2 Activation of ESX Gene Expression. (2002) Oncogene 30: 3934-3938.

Scott GK, Chang C-H, Erny K, Xu F, Fredericks WJ, Rauscher FJ, Thor AD, and Benz CC. Ets Regulation of the ErbB2 Promoter. (2000) Oncogene 19: 6490-6502.
 
Lin CS, Lau A, Yeh CC, Chang C-H, and Lue TF. Upregulation of L-
Plastin Gene by Testosterone in Breast and Prostate Cancer Cells: Identification of Three Cooperative Androgen Receptor-binding Sequences. (2000) DNA Cell Biol. 19: 1-7.

Chang C-H, Scott GK, Baldwin MA, and Benz CC. Exon 4-encoded Acidic Domain in the Epithelium-restricted Ets Factor, ESX, confers Potent Transactivating Capacity and binds to TATA-binding Protein (TBP). (1999) Oncogene 18: 3682-3695. 

Neve R, Chang C-H, Scott GK, Wong A, Friis RR, Hynes NE, and Benz CC. The Epithelium-specific Ets Transcription Factor ESX is Associated with Mammary Gland Development and Involution. (1998) FASEB J. 12: 1541-1550.

Liang X, Lu B, Scott GK, Chang C-H, Baldwin MA, and Benz CC. Oxidant Stress Impaired DNA-binding of Estrogen Receptor from Human Breast Cancer. (1998) Mol. Cell. Endocrinol. 146: 151-161.

Lu B, Liang X, Scott GK, Chang C-H, Baldwin MA, Thomas T, and Benz CC. Polyamine Inhibition of Estrogen Receptor DNA-Binding and Ligand-Binding Functions. (1998) Breast Cancer Res. Treat. 48: 243-257.

Chang C-H, Scott GK, Kuo W-L, Xiong X, Suzdaltseva Y, Park JW, Sayre P, Erny K, Gray JW, and Benz CC. ESX: A Structurally Unique Ets Overexpressed Early during Human Breast Tumorigenesis. (1997) Oncogene 14: 1617-1622.

Lin C-S, Chang C-H, and Huynh Truc. The Murine L-plastin Gene Promoter: Identification and Comparison with the Human L-plastin Gene Promoter. (1997) DNA Cell Biol. 16: 9-16.

Benz CC, O agan RC, Richter B, Scott GK, Chang C-H, Xiong X, Chew K, Ljung BM, Edgerton S, Thor A, and Hassell JA. HER-2/neu and the Ets Transcription Activator PEA3 are Coordinately Upregulated in Human Breast Cancer. (1997) Oncogene 15: 1513-1525.

¡@

  

¡@
  Introduction | Announcement | Members | Projects | Resources | Contact | back to top

Designed by CYC

  GEL, Institute of Bioinformatics, National Yang-Ming University. © 2002