Molecular & Cell Biology

Course description

An introduction to the theory and practice of Molecular and Cell Biology.

Goals for the course: The course will familiarize students with the principles and tools of contemporary molecular & cell biology. By the end of the course, students will have a working knowledge of a variety of topics important in molecular & cell biology, and a grasp of the underlying principles that is adequate for them to evaluate and use new tools as they arise in the future.

Course Requirements:

• Prerequisites: A familiarity with the concepts of biology, basic chemistry, and comfort using computers and the internet
  Although there are no formal course prerequisites, you should have at least one prior upper division undergraduate course (or better) in each of biology, chemistry and computer skills.

• For this course, students will be required to read in advance a (or several) particular chapter(s) of the textbook. Additional reading material may also be assigned by each instructor.

• Textbook: The Cell: A Molecular Approach, by Geoffrey M. Cooper. (2000).    The book is available in the Yi-Hsient Bookstore. 

• Supplementary text:
  (1) Molecular Biology of The Cell, by Bruce Alberts et. al. (2002).
  (2) Cell and Molecular Biology: concepts and experiments, by Gerald Karp (2002).
  (3) Molecular Cell Biology, by Harvey Lodish et. al. (1999).
  (4) Genes VII, by Benjamin Lewin (1999).
  These are also available from the Yi-Hsient Bookstore.

• Access to a computer with an internet connection

Syllabus & Lecture Notes

The lecture notes will be available in Acrobat (pdf) format.

1. 授課對象：遺傳諮詢推廣教育碩士學分班　　　　　　　 時　　間：每週六上午10:10-12:00 地　　點：傳醫大樓乙棟四樓401室		負責教師姓名：張傳雄                                    聯 絡 電 話 ：(02) 28267316                                   鍾明怡教師: (02) 28712121 ext. 3265
   日期	講題		時數	教師姓名（中文）	上課投影片	Reading Assignments from Textbook
   2/22 3/1 3/8 3/15 3/22 3/29 4/5 4/12 4/19 4/26 5/10 5/17 5/31 5/31 6/7 6/14 6/14 6/21 6/27(五)	Course Introduction. Molecular Building Blocks of Cells        DNA Replication, Repair and Rearrangement Transcription and its Regulation Translation and its Regulation The Nucleus Protein Sorting and Transport Holiday Mitochondria Midterm Exam Cell Cycle and Growth Regulation (starts at 9:00 am) Cell Division (starts at 9:00 am) Cell Communication & Signal Transduction (starts at 9 am) The Cytoskeleton and Cell Movement (starts at 9:00 am) Cell Junctions and Cell Adhesion (starts at 9:00 am) The Immune System (starts at 10:00 am) Germ Cells and Fertilization (starts at 9:00 am) Development of Multicellular Organisms (starts at 9:00 am) No class Final Exam (starts at 4:30 pm in 遺傳所 Room 552)		2 2 2 2 2 2   2 2 2 2 2 2 2 2 2 2 2	張傳雄、鍾明怡 傅淑玲 蘇宗笙 林茂榮 鍾明怡 鄭明媛   鍾明怡 鍾明怡 吳茂青 張傳雄 張傳雄 張傳雄 張傳雄 吳茂青 張傳雄 張傳雄 張傳雄	B/W; Color B/W; Color B/W; Color B/W; Color B/W; Color B/W; Color   B/W; Color Midterm; Key B/W; Color B/W; Color B/W; Color B/W; Color B/W; Color B/W; Color B/W; Color B/W; Color Final; Key	Chapters 1, 2, 3, & 4 Chapter 5 Chapter 6 Chapter 7 Chapter 8 Chapter 9   Chapter 10   Chapter 11 Chapters 12 & 13 Chapter 14 Chapter 14 Chapter 12 Chapter 14 Chapter 14 Chapter 15

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   Grading

   Problem sets: There will be two take home problem sets, each of which is expected to take you several hours of work. These problem sets are intended to give you hands on experience with the work of molecular & cell biology, and should be learning experiences as well as evaluation tools. Problem sets aim at solidifying the concepts acquired in the lectures.

   Problem sets

   Problem sets and solutions will be posted here.

   Problem Set 1	Problem Set 2
   PS 1 Solutions	PS 2 Solutions

   Midterm

   Midterm:  There will be an in-class Midterm exam on April 19, and it will be worth four problem sets.

   Final

   Final:  There will be an in-class final exam on June 28, and it will be worth four problem sets.

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   Web sites

   Sites mentioned in class

   • Local Resources

   • Key MCB tools and sites